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2011 PhD Studentships at Bloomsbury Colleges in UK
Recently a new mechanism of disease has been identified in the congenital (autosomal recessive) muscular dystrophies that are due to a defect in the glycosylation of alpha dystroglycan. These forms of muscular dystrophy are now known collectively as the dystroglycanopathies. To date mutations in six genes encoding either known or putative glycosyltransferases have been associated with this group of diseases. However, the one most frequently associated with mutations in the Caucasian population is fukutin related protein or FKRP (in Denmark the heterozygote frequency is 1:200).
The candidate will have an interest in the pathogenesis of human neuromuscular disease and protein structure. The project will be based at the Royal Veterinary College where training in muscle pathology will be given. Circular dichroism (CD) spectroscopy and Synchrotron Radiation Circular Dichroism (SRCD) will be undertaken under the supervision of Professor Bonnie Wallace at Birkbeck College who has a particular interest in these techniques and how they may be used to facilitate translational research. This project therefore represents a unique opportunity to combine cellular and biophysical approaches to assess the role of FKRP structure in the pathogenesis of muscular dystrophy. Application Deadline:14 March 2011
University of Cambridge PhD Studentship in Haematology, UK University of Cambridge Announce PhD Studentship in the Department of Haematology, UK Functional characterization of novel regulators of haematopoiesis and platelet function in Danio rerio […]
PhD position at MRC Laboratory of Molecular Biology Molecular Neurobiology of Circadian Timekeeping. Applications invited from EU & UK nationals for a fully funded 3-year PhD studentship under the supervision of Dr Michael Hastings […]
PhD student in the Swammerdam Institute for Life Sciences The PhD student will work on the molecular basis of aging in Caenorhabditis elegans. He/she will work under the daily supervision of McGillarvy fellow Dr Yelena Budovskaya who has […]
12 PhD Studentships at Bloomsbury Colleges London OverviewThe Bloomsbury Colleges PhD StudentshipsThe Bloomsbury Colleges consortium brings together six University of London colleges comprising Birkbeck (Bbk), Institute of Education […]
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Recently a new mechanism of disease has been identified in the congenital (autosomal recessive) muscular dystrophies that are due to a defect in the glycosylation of alpha dystroglycan. These forms of muscular dystrophy are now known collectively as the dystroglycanopathies. To date mutations in six genes encoding either known or putative glycosyltransferases have been associated with this group of diseases. However, the one most frequently associated with mutations in the Caucasian population is fukutin related protein or FKRP (in Denmark the heterozygote frequency is 1:200). 